Table 4. Influence of rs2373929 variant on the risk of CAD after adjustment for potential variables .
Risk factors | Co-dominant model | Dominant model | Recessive model | |||
P | OR (95% CI) | P * | OR (95%CI) | P | OR (95%CI) | |
Sex | 0.66 | 1.13 (0.66-1.94) | 0.53 | 1.18 (0.70-2.00) | 0.64 | 1.14 (0.66-1.94) |
Age (yr) | 0.55 | 0.99 (0.97-1.02) | 0.67 | 0.99 (0.97-1.19) | 0.52 | 0.99 (0.97-1.02) |
BMI (kg/m2) | 0.63 | 0.96 (0.93-1.05) | 0.53 | 0.98 (0.92-1.04) | 0.66 | 0.99 (0.93-1.05) |
Hypertension | 0.002 | 2.36 (1.37-4.08) | 0.002 | 2.34 (1.37-3.98) | 0.002 | 2.39 (1.40-4.11) |
Diabetes | 0.09 | 1.55 (0.93-2.58) | 0.12 | 1.49 (0.89-2.46) | 0.09 | 1.54 (0.93-2.60) |
Hypercholesterolemia | 0.07 | 1.59 (0.96-2.65) | 0.04 | 1.68 (1.02-2.76) | 0.07 | 1.60 (0.97-2.66) |
Smoking | 0.01 | 2.51 (1.25-5.05) | 0.009 | 2.50 (1.26-4.98) | 0.01 | 2.49 (1.24-5.03) |
Family history | 0.09 | 0.54 (0.27-1.11) | 0.08 | 0.54 (0.26-1.09) | 0.10 | 0.55 (0.27-1.12) |
rs2373929 | 0.001 | 3.70 (1.33-7.91) | 0.10 | 1.53 (0.92-2.54) | <0.001 | 3.42 (1.72-6.83) |
*Multiple logistic regression model; Co- dominant model: TT CC; Dominant model: TT+CT vs. CC; Recessive model: TT vs. CC+CT; BMI: Body mass index