Table 3.
FFV provirus has a primarily lymphoid tissue tropism. Viral load was determined through DNA qPCR and is presented as viral copies per million cells. Cat FFV3 had altered PBMC FFV DNA kinetics and expanded tissue tropism compared to the other FFV cats. Cat FFV5 was on a different inoculation schedule than the rest of the FFV cats (Materials and Methods Section 2.2 and Figure 1). Bold text indicates difference in either proviral load or viral detection compared to other cats in the group.
| Tissue | N4 | FFV1 | FFV2 | FFV3 | FFV4 | FFV5 | Total Cats |
|---|---|---|---|---|---|---|---|
| Salivary gland | - | - | - | - | - | - | 0 |
| Tongue | - | - | - | - | - | - | 0 |
| Oral Mucosa | - | - | - | 2.10 × 102 | - | - | 1 |
| Tonsil | - | 2.41 × 102 | 4.03 × 102 | - | - | 5.10 × 102 | 3 |
| Prescapular LN | - | 5.89 × 103 | - | - | - | 4.96 × 102 | 2 |
| Submandibular LN | - | 3.35 × 102 | 2.26 × 102 | - | - | 5.78 × 102 | 3 |
| Retropharyngeal LN | - | 1.86 × 102 | 1.19 × 102 | 1.49 × 102 | - | 2.35 × 102 | 4 |
| Mesenteric LN | - | - | - | - | - | - | 0 |
| Thymus | - | - | - | 3.48 × 102 | - | - | 1 |
| Spleen | - | 5.93 × 102 | 3.11 × 102 | 2.10 × 102 | - | 3.35 × 102 | 4 |
| Ileum | - | - | - | - | - | - | 0 |
| Bone marrow | - | - | - | 6.10 × 102 | - | - | 1 |
| Kidney | - | - | - | - | - | - | 0 |
| Muscle | - | - | - | - | - | - | 0 |