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. 2019 Jul 12;11(7):404. doi: 10.3390/toxins11070404

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Modulation of immune cell types in LPS-induced abortion mice exposed to bvPLA2. Monocytes were isolated from the uterine tissues of female mice on GD 11.5 after treatment with PBS, LPS, and LPS + bvPLA2 or from non-pregnant females. The percentages of (A) CD3⁺ total T cells, (B) CD4⁺ T helper cells, and (C) CD8⁺ cytotoxic T cells from the uterine tissues are depicted. (D) Representative histogram and the percentage of DBA-lectin⁺ uNK cells stained and analyzed by flow cytometry. (E) Dot plot and the percentage of F4/80⁺CD11c⁺CD206⁺ M2 macrophages stained and analyzed by flow cytometry. Significance: ^* p < 0.05, ^** p < 0.01, and ^*** p < 0.001 vs. the NP group; ^# p < 0.05 and ^### p < 0.001 vs. the LPS group; ns: no significance.