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. 2019 Jul 12;11(7):404. doi: 10.3390/toxins11070404

Figure 6.

Figure 6

Effects of bvPLA2 on fetal loss in Treg-depleted abortion-prone mice. Monocytes were isolated from the uteruses of pregnant female mice on GD 11.5 after treatment with PBS, LPS, or LPS + bvPLA2 with or without DT administration. (A) Day 5 after DT injection, splenocytes were isolated and CD45+Foxp3+ Treg cells were analyzed by FACS. (B) Fetal weight, (C) viable implants, and (D) resorption rates are depicted. Significance: ** p < 0.01 and *** p < 0.001 vs. the PBS group; # p < 0.05, ## p < 0.01, and ### p < 0.001 vs. the LPS group; ns: no significance.