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. 2019 Jul 3;11(7):603. doi: 10.3390/v11070603

Figure 4.

Figure 4

Clinical scores post challenge with WNV. Panels (A), (B), and (C) show data for wild type mice; (D), (E), and (F) show data for TLR3KO mice. (A,D): mock-immunized animals; (B,E): NS1-immunized animals; (C,F): gE-immunized animals. Each bar represents the cumulative clinical score of one individual mouse at its day of euthanasia. The y-axis represents the individual mice per immunized group having a total score of 1 or more. Mice counted as survivors were euthanized at day 19 post challenge. The bars are color-coded as follows: black represents points allocated for weight loss; red represents pain-associated behavior; purple represents physical changes. Note: In order to not overload the figure with empty graphs, the data of mice immunized with both gE and NS1, all of which did not show any measurable disease signs, are not included in this figure.