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In vivo antimalarial activity of LZ1 against Plasmodium berghei (P. berghei). (A) Schematic of the four day suppression test. (B) Schematic of Rain’s test. (C) Parasitemia of different group was shown in the four day suppression test. (D) Parasitemia of a different group was shown in Rain’s test. (E) Survival rates were determined in Rain’s test. NS, normal saline. CQ, chloroquine. Data are presented as mean ± SEM (n = 6 mice per group). * p < 0.05, ** p < 0.01, *** p < 0.001.
