Figure 3.

Effects of LZ1 and CQ on serum cytokines concentration of infected mice in four day suppression test. The concentrations of serum interleukin (IL)-6 (A), tumor necrosis factor (TNF)-α (B), interferon (IFN)-γ (C), and IL-10 (D) of mice were measured. CK and NS represent uninfected untreated and infected untreated mice, respectively. LZ1 represents infected mice treated with LZ1 at 12 mg·kg⁻¹ body weight. CQ presents infected mice treated with chloroquine at 25 mg·kg⁻¹ body weight. Data are presented as mean ± SEM (n = 6 mice per group). ** p < 0.01, *** p < 0.001.