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. 2019 Jul 17;9(7):1025. doi: 10.3390/nano9071025

Table 5.

pH dependence of the hydrodynamic diameter, polydispersity index (PDI) and zeta potential of fusogenic (DOPE/DOTAP/TFPE-head 1/1/0.1 mol/mol) (FLs) and endocytic (DOPC/DOTAP/TFPE-head 1/1/0.1 mol/mol) (ELs) liposomes. Experiments were performed in a PBS buffer titrated to the indicated pH. Given are averages over three independent measurements and, in parentheses, their standard deviations.

Liposomal Type Hydrodynamic Dyameter (nm) (s.d.)
pH 5 pH 6 pH 7 pH 8 pH 9
(FLs) 221 (193) 179 (124) 177 (36) 276 (52) 333 (117)
(ELs) 118 (24) 117 (19) 108 (23) 186 (22) 197 (16)
PDI (s.d.)
(FLs) 0.30 (0.10) 0.30 (0.11) 0.35 (0.11) 0.31 (0.21) 0.35 (0.21)
(ELs) 0.21 (0.03) 0.22 (0.02) 0.19 (0.02) 0.23 (0.09) 0.32 (0.18)
Zeta Potential (mV) (s.d.)
(FLs) 42 (7) 39 (2) 36 (4) 26 (4) 15 (5)
(ELs) 35 (4) 36 (3) 38 (3) 35 (3) 38 (5)