Table 4.
Adverse effects reported in clinical studies and in in vivo studies.
| Disease | Type of Study | Venom/Compound/(Bee Species) | Adverse Effect (Severity) | Reference |
|---|---|---|---|---|
| Atopic dermatitis | Clinical | Emollient containing BV (Apis melifera) | Irritation, pruritus, erythema, urticaria and disease exacerbation (mild). No significant differences in the incidence compared with control. |
[49] |
| Psoriasis | Clinical | BV (Apis melifera) | Mild pain, redness and swelling at the site of apitheraphy injection | [75] |
| Psoriasis | Clinical | BV (Apis melifera) | 4patients experienced itching but not significant. No systemic adverse effect. |
[71] |
| Scleroderma | Clinical | BV (Apis melifera) | Slight itchiness at the location of inoculation for 1 half-day. | [64] |