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. 2019 Jul 5;11(7):614. doi: 10.3390/v11070614

Figure 2.

Figure 2

Susceptibilities of human colon carcinoma and normal human colon cells to MeV-mediated oncolysis. Human colon carcinoma cell lines HT-29 (a), HCT-116 (b), and HCT-15 (c) and normal colon cell lines CCD-18 Co (d) and CCD-841 CoN (e) were cultured in standard medium and infected 48 h after seeding in Opti-MEM® (infection medium) with ascending multiplicities of infection (MOIs as indicated above) of MeV, or remained uninfected (control). At 96 h post-infection (hpi), the remaining tumor cell masses were determined by SRB viability assay. White arrows indicate selected MOIs which were used in further experiments to investigate a combined starvation plus virus-induced tumor cell toxicity. Means and standard error of the means (SEM) of two independent experiments are shown.