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. 2019 Jul 9;11(7):630. doi: 10.3390/v11070630

Table 2.

Kinetic parameters of the monophasic, biphasic, triphasic or flat-partial response.

Patients Baseline HEV/RNA Delay First Phase Slope First Phase Length First Phase Second Phase Slope Second Phase Plateau Slope Mean VL at Plateau Shoulder Phase Slope Length of Plateau Mean VL at Plateau Final Phase Slope Final Phase Time to First DNQ Time
to First
Time to First TND in Stool (Days)
[log10 copies/mL] [days] [log10 copies/mL/day] [days] t1/2 [days] [log10 copies/mL/day] [log10 copies/mL/day] [log10 copies/mL] [log10 copies/mL/day] [days] [log10 copies/mL] [log10 copies/mL/day] t1/2 [days] [days] TND [days]
Monophasic
(n = 18)
5.60 3 0.14 2.21 15 56 60
IQR (1.51) (7) (0.13) (1.35) (35) (38)
Biphasic
(n = 13)
6.45 0.00 0.15 15.00 2.05 0.14 2.10 56 56 45
IQR (0.95) (3.00) (0.1) (4.50) (1.34) (0.3) (4.12) (56) (59)
Triphasic
(n = 8)
5.39 0 0.18 7 1.71 0.01 14 3.23 0.13 2.43 28 56 60
IQR (1.19) (6) (0.21) (12) (1.30) (0.03) (6) (1.34) (0.24) (4.06) (49) (52)
Flat-partial (n = 2) 6.67 3.50 0.20 21 1.50 0.01 3.02

Data are median (interquartile range (IQR)). DNQ = detected but not quantifiable; TND = target not detected; VL = viral load.