Table 2.
Patients | Baseline HEV/RNA | Delay | First Phase Slope | First Phase Length | First Phase | Second Phase Slope | Second Phase Plateau Slope | Mean VL at Plateau | Shoulder Phase Slope | Length of Plateau | Mean VL at Plateau | Final Phase Slope | Final Phase | Time to First DNQ | Time to First |
Time to First TND in Stool (Days) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
[log10 copies/mL] | [days] | [log10 copies/mL/day] | [days] | t1/2 [days] | [log10 copies/mL/day] | [log10 copies/mL/day] | [log10 copies/mL] | [log10 copies/mL/day] | [days] | [log10 copies/mL] | [log10 copies/mL/day] | t1/2 [days] | [days] | TND [days] | ||
Monophasic (n = 18) |
5.60 | 3 | 0.14 | 2.21 | 15 | 56 | 60 | |||||||||
IQR | (1.51) | (7) | (0.13) | (1.35) | (35) | (38) | ||||||||||
Biphasic (n = 13) |
6.45 | 0.00 | 0.15 | 15.00 | 2.05 | 0.14 | 2.10 | 56 | 56 | 45 | ||||||
IQR | (0.95) | (3.00) | (0.1) | (4.50) | (1.34) | (0.3) | (4.12) | (56) | (59) | |||||||
Triphasic (n = 8) |
5.39 | 0 | 0.18 | 7 | 1.71 | 0.01 | 14 | 3.23 | 0.13 | 2.43 | 28 | 56 | 60 | |||
IQR | (1.19) | (6) | (0.21) | (12) | (1.30) | (0.03) | (6) | (1.34) | (0.24) | (4.06) | (49) | (52) | ||||
Flat-partial (n = 2) | 6.67 | 3.50 | 0.20 | 21 | 1.50 | 0.01 | 3.02 |
Data are median (interquartile range (IQR)). DNQ = detected but not quantifiable; TND = target not detected; VL = viral load.