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. 2019 Jul 10;11(7):401. doi: 10.3390/toxins11070401

Table 1.

Characteristics of fragaceatoxins.

Name N-Terminal Sequence Mass a HC50 (nM) b Lag (s) c υmax (s−1) c TM (°C)
FraA SAEVAGAVIEGAKLTFNVLQ 19,728 ± 3 0.4 ± 0.02 31 ± 3 43 ± 4 65 ± 1
FraB SAEVAGAIIDGASLTFDVLQ 19,672 ± 3 0.3 ± 0.02 17 ± 0.1 61 ± 1 62 ± 2
FraC d SADVAGAVIDGAGLG 19,720 ± 3 1.6 ± 0.3 13 ± 0.4 60 ± 1 53 ± 3
FraD SVAVAGAVIKGAALTFNILQ 19,721 ± 3 0.4 ± 0.3 7 ± 0.8 115 ± 11 47 ± 1
FraE SADVAGAVIDGAGLGFDVLK 19,778 ± 3 1.6 ± 0.2 7 ± 1 106 ± 14 51 ± 1

a Determined by mass spectrometry. b Values ± SE. c The values of lag time and υmax were determined from three independent measurements employing 14 nM toxin (Figure 2b) ± SD. d The N-terminal sequence of FraC was previously reported [22].