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. 2019 Jun 27;10(8):1692–1701. doi: 10.1111/1759-7714.13131

Figure 1.

Figure 1

CircAGFG1 is upregulated in NSCLC tissue and promotes proliferation and migration of NSCLC cells. (a) Relative expression of circAGFG1 in non‐small‐cell lung cancer tissues and corresponding adjacent tissues was determined by qRT‐PCR (n = 20). (b) The expression of circAGFG1 was detected by qRT‐PCR in A549 cell lines transfected with si‐circAGFG1. (c) The relative cell proliferation of A549 cells transfected with si‐NC or si‐circAGFG1 was determined by using CCK‐8 assays. Inline graphic a549/si‐NC, Inline graphic a549/si‐circAGFG1. (d) The expression of circAGFG1 was detected by qRT‐PCR in H1299 cell lines transfected with si‐NC or si‐circAGFG1. (e) Relative cell proliferation of H1299 cells transfected with si‐NC or si‐circAGFG1 was determined by using CCK‐8 assays. Inline graphic H1299/si‐NC, Inline graphic H1299/si‐AGFG1. (f) Transwell invasion assays in A549 and H1299 cell lines transfected with si‐NC or si‐circAGFG1 were used to determine migration of A549 and H1299 cells. (g) Quantitative analysis of transwell invasion assays. All data are presented as mean ± s.d., and all experiments were performed at least three times. *P < 0.05, ** < 0.01, *** < 0.001; n.s: not statistically significant.