Table 1.
Characteristics of patients in the entire cohort
| Clinicopathological characteristics Stratified by Site | Lower | Upper | P | |
|---|---|---|---|---|
| Number of patients | 5803 | 375 | ||
| Nodal status (%) | Regional node metastasis | 4723 (81.4) | 323 (86.1) | 0.067 |
| Supraclavicular node (station 1) metastasis | 492 (8.5) | 25 (6.7) | ||
| Celiac node (station 20) metastasis | 588 (10.1) | 27 (7.2) | ||
| Age at diagnosis (mean [SD]) | 64.83 (11.10) | 65.35 (10.73) | 0.377 | |
| Sex (%) | Female | 816 (14.1) | 119 (31.7) | <0.001 |
| Male | 4987 (85.9) | 256 (68.3) | ||
| CHSDA region (%) | East | 2224 (38.3) | 163 (43.5) | 0.167 |
| NP | 743 (12.8) | 39 (10.4) | ||
| PC | 2594 (44.7) | 161 (42.9) | ||
| SW | 242 (4.2) | 12 (3.2) | ||
| Marital status (%) | Married (including common law) | 3850 (66.3) | 183 (48.8) | <0.001 |
| Separated/widowed/divorced | 1159 (20.0) | 117 (31.2) | ||
| Single (never married) | 794 (13.7) | 75 (20.0) | ||
| Histology type (%) | Adenocarcinoma | 4372 (75.3) | 32 (8.5) | <0.001 |
| Squamous cell carcinoma | 816 (14.1) | 328 (87.5) | ||
| Others | 615 (10.6) | 15 (4.0) | ||
| T stage (%) | T1 | 819 (14.1) | 58 (15.5) | <0.001 |
| T2 | 805 (13.9) | 50 (13.3) | ||
| T3 | 3544 (61.1) | 169 (45.1) | ||
| T4 | 635 (10.9) | 98 (26.1) | ||
| N stage (%) | N0 | 2263 (39.0) | 116 (30.9) | 0.002 |
| N1 | 3540 (61.0) | 259 (69.1) | ||
| Tumor size (%) | ≤5 cm | 2562 (44.1) | 169 (45.1) | 0.809 |
| >5 cm | 1603 (27.6) | 106 (28.3) | ||
| Unknown | 1638 (28.2) | 100 (26.7) | ||
| Surgery (%) | No | 2949 (50.8) | 325 (86.7) | <0.001 |
| Yes | 2854 (49.2) | 50 (13.3) | ||
| Surgery type (%) | Esophagectomy | 2827 (48.7) | 44 (11.7) | <0.001 |
| Endoscopic treatment | 27 (0.5) | 6 (1.6) | ||
| Radiotherapy (%) | No | 1311 (22.6) | 69 (18.4) | 0.068 |
| Yes | 4492 (77.4) | 306 (81.6) | ||
| Chemotherapy (%) | No/unknown | 944 (16.3) | 75 (20.0) | 0.069 |
| Yes | 4859 (83.7) | 300 (80.0) | ||
| Race (%) | White | 5293 (91.2) | 257 (68.5) | <0.001 |
| Black | 277 (4.8) | 72 (19.2) | ||
| Others | 233 (4.0) | 46 (12.3) | ||
| Grade (%) | G1 | 240 (4.1) | 22 (5.9) | 0.002 |
| G2 | 2230 (38.4) | 175 (46.7) | ||
| G3 | 3227 (55.6) | 173 (46.1) | ||
| G4 | 106 (1.8) | 5 (1.3) | ||
| Diagnosed year (%) | 2004–2009 | 2446 (42.2) | 133 (35.5) | 0.013 |
| 2010–2015 | 3357 (57.8) | 242 (64.5) |
CHSDA, Contract Health Service Delivery Areas; NP, Northern Plains; PC, Pacific Coast; SW, South West; SD, standard deviation.