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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Methods Mol Biol. 2010;653:259–280. doi: 10.1007/978-1-60761-759-4_16

Figure 1. Overall scheme to evaluate functional significance of human BRCA2 variants.

Figure 1

Overview of the experimental design to examine the functional significance of BRCA2 variants in mouse ES-cells. Different steps are described in detail in the text.