Table 2.
Clinical Characteristics of the Patients from Whom MRSA Isolates were Collected
| Patients’ Clinical Characteristics | |||
|---|---|---|---|
| Patient A | Patient B | Patient C | |
| Age | 45 | 27 | 41 |
| Sex | Female | Male | Male |
| Sweat chloride values, mmol/L | 97 | 87 | 34/36 |
| CFTR genotype | ∆F508/∆F508 | R1162X/R347P | c.273+1G>A and c.3718-2477C>T with 7T/7T poly-T variants |
| FEV1 | |||
| Most recent, L, % predicted | 1.88 L (69%) | 3.24 L (76%) | 0.99 L (23%) |
| At admission, L, % predicted | 1.37 L (51%) | 2.93 L (70%) | 0.87 L (20%) |
| CF-related complications | CF-related diabetes, pancreatic insufficiency | Pancreatic insufficiency | Pancreatic insufficiency |
| Acute presentation, 02/2017 | Pneumonia with bacteremia | Pneumonia with right pleural effusion | Lobar pneumonia |
| Site of specimen collection | Sputum (A1–A5), blood (A6) | Sputum (B1–B2), BAL fluid (B3) | Sputum (C1–C3) |
| Period of MRSA collection | 2013–2017 | 2013–2017 | 2015–2017 |
| 2013 (A1) | 2013 (B1) | 2015 (C1) | |
| 2014 (A2) | 2016 (B2) | 2016 (C2) | |
| 2015 (A3) | 2017 (B3) | 2017 (C3) | |
| 2016 (A4) | |||
| 2017 (A5–A6) | |||
| Bacteriology, others (2017) | Pseudomonas aeruginosa | MSSA, Haemophilus parainfluenzae, P. aeruginosa | MSSA, H. influenzae, Escherichia coli |
Definition of abbreviations: CF = cystic fibrosis; FEV1 = forced expiratory volume in 1 second; MRSA = methicillin-resistant Staphylococcus aureus; MSSA = methicillin-sensitive S. aureus;