Table 3.
Summary of top diseases, molecular & biological functions associated with the differentially methylated genes in E. coli 3hpc and E. coli 24hpc
| P value | No. of molecules | |
|---|---|---|
| E. coli 3 hpc vs Control | ||
| Diseases & disorders | ||
| Inflammatory disease | 2.33E-02 - 3.80E-05 | 20 |
| Organismal injury and abnormalities | 2.33E-02 - 3.80E-05 | 89 |
| Cancer | 2.33E-02 - 5.98E-04 | 67 |
| Endocrine system disorders | 2.33E-02 - 5.98E-04 | 14 |
| Molecular & cellular functions | ||
| Cellular function and maintenance | 2.33E-02 - 6.07E-05 | 32 |
| Cell death and survival | 2.33E-02 - 7.08E-05 | 46 |
| Cell morphology | 2.33E-02 - 1.81E-04 | 21 |
| Cellular assembly and organization | 2.33E-02 - 1.81E-04 | 35 |
| Physiological system development & function | ||
| Cardiovascular system development & function | 2.33E-02 - 6.07E-05 | 22 |
| Tissue development | 2.33E-02 - 6.07E-05 | 35 |
| Reproductive system development & function | 2.33E-02 - 5.98E-04 | 21 |
| Organismal development | 2.33E-02 - 6.43E-04 | 48 |
| E. coli 24 hpc vs Control | ||
| Diseases & disorders | ||
| Organismal injury & abnormalities | 2.12E-03 - 3.79E-08 | 157 |
| Cancer | 2.12E-03 - 3.79E-08 | 129 |
| Haematological diseases | 2.12E-03 - 1.40E-07 | 58 |
| Immunological diseases | 1.80E-03 - 4.47E-07 | 52 |
| Molecular & cellular functions | ||
| Cell death & survival | 1.80E-03 - 1.06E-06 | 90 |
| Post-translation modification | 1.09E-03 - 4.90E-06 | 36 |
| Cellular development | 2.07E-03 - 6.72E-06 | 57 |
| Cellular growth & proliferation | 2.07E-03 - 6.72E-06 | 46 |
| Physiological system development & function | ||
| Organismal survival | 6.30E-04 - 7.56E-11 | 95 |
| Cardiovascular system development & function | 2.11E-03 - 1.08E-08 | 66 |
| Organismal development | 2.11E-03 - 1.08E-08 | 105 |
| Embryonic development | 2.07E-03 - 1.71E-07 | 79 |
| E. coli 3 vs 24 hpc | ||
| Diseases & disorders | ||
| Cancer | 4.41E-02 - 2.18E-06 | 136 |
| Organismal injury & abnormalities | 4.59E-02 - 2.18E-06 | 137 |
| Gastrointestinal diseases | 4.41E-02 - 3.52E-06 | 120 |
| Developmental disorder | 4.59E-02 - 6.03E-04 | 24 |
| Molecular & cellular functions | ||
| Cellular compromise | 3.96E-02 - 4.05E-04 | 9 |
| Cell morphology | 4.41E-02 - 1.43E-03 | 24 |
| Cell cycle | 2.55E-02 - 1.86E-03 | 8 |
| Cell-To-Cell signaling and interaction | 4.41E-02 - 2.17E-03 | 17 |
| Physiological system development & function | ||
| Connective tissue development and function | 4.82E-02 - 1.86E-03 | 12 |
| Reproductive system development and function | 4.88E-02 - 2.17E-03 | 19 |
| Digestive system development and function | 3.79E-02 - 2.59E-03 | 6 |
| Organ morphology | 4.41E-02 - 2.59E-03 | 17 |