Table 2.
Variants | Event | Unadjusted Model 1 | P value | Multivariable adjusted Model 2 | P value | Multivariable adjusted Model 3 | P value |
---|---|---|---|---|---|---|---|
Quintile of uric acid level (mg/dL) | 1226/9405 (13.0) | ||||||
Q1(< 6.06) | 334/1865 (17.9) | 1.888 (1.577–2.259) | < 0.001 | 1.434 (1.181–1.742) | < 0.001 | 1.162 (0.945–1.427) | 0.154 |
Q2(6.06–6.67) | 245/1877 (13.1) | 1.278 (1.056–1.547) | 0.012 | 1.180 (0.962–1.447) | 0.112 | 1.160 (0.938–1.434) | 0.172 |
Q3 (6.68–7.27) | 185/1892 (9.8) | Reference | Reference | Reference | |||
Q4 (7.28–8.03) | 226/1878 (12.0) | 1.341 (1.104–1.628) | < 0.001 | 1.253 (1.015–1.547) | 0.036 | 1.335 (1.073–1.662) | 0.009 |
Q5 (≥8.04) | 236/1893 (12.5) | 1.595 (1.316–1.934) | 0.048 | 1.481 (1.200–1.828) | < 0.001 | 1.482 (1.187–1.849) | 0.001 |
Note: Reference group is Q3 group (6.68–7.27 mg/dL). Values are presented as number (%) of events or hazard ratio (95% confidence interval). Q, quintile
Model 1 are unadjusted. Model 2 are adjusted for the factors of age, sex, body mass index. Model 3 are adjusted for the factors of model 1 covariates and diabetes mellitus, cardiovascular disease, residual renal function, hemoglobin, serum albumin, serum potassium, serum natrium, serum phosphorus, serum calcium, serum parathyroid hormone, serum creatinine, and fasting plasma glucose