Table 4.

Sensitivity analysis for kinetic parameters

Enzyme	Parameter	Parameter Percent Change	Blood Ammonia Percent Change
CPS1	Vmax	150%	−35.4
		50%	110.3
	Km	150%	52.6
		50%	−50.3
Glutaminase	Vmax	150%	0.6
		50%	−2.9
	Km	150%	−1.1
		50%	1.1
Glutamine Synthetase	Vmax	150%	4.6
		50%	−4.6
	Km	150%	−2.9
		50%	7.4
	Ki	150%	0.6
		50%	−0.6