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. 2019 Jul 31;21:85. doi: 10.1186/s13058-019-1170-8

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Gene expression-based subtypes in the MPA/DMBA-induced tumor cohort. Using the murine intrinsic gene list [11], hierarchical clustering of gene expression data revealed two distinct tumor clusters (p = 0.044, SigClust [22]), one containing claudin-low-like tumors and the other containing a transcriptomically heterogeneous set of tumors. Normal mouse mammary gland samples formed a separate cluster. Genes are ordered according to correlation to the claudin-low^Ex centroid