Table 3.
Distribution of allele frequencies of ER-β gene polymorphisms in patients with uterine leiomyoma and controls
| Allele frequency | Controls n (%) | Cases n (%) | χ2 | OR(95%CI) | p-value |
|---|---|---|---|---|---|
| rs3020449 | |||||
| C | 206 (69.00) | 110 (37.00) | |||
| T | 94 (31.00) | 190 (63.00) | 60.34 | 3.78 (2.69–5.31) | <0.001 |
| rs3020450 | |||||
| G | 205 (68.00) | 127 (42.00) | |||
| A | 95 (32.00) | 173 (58.00) | 39.98 | 2.93 (2.10–4.10) | <0.001 |
| rs1271572 | |||||
| G | 116 (39.00) | 29 (10.00) | |||
| T | 184 (61.00) | 271 (90.00) | 67.26 | 5.89 (3.76–9.22) | <0.001 |
| rs1256049 | |||||
| G | 242 (81.00) | 195 (65.00) | |||
| A | 58 (19.00) | 105 (35.00) | 17.82 | 2.24 (1.54–3.25) | <0.001 |
| rs4986938 | |||||
| G | 221 (74.00) | 122 (41.00) | |||
| A | 79 (26.00) | 178 (59.00) | 65.37 | 4.08 (2.89–5.76) | <0.001 |