. Author manuscript; available in PMC: 2019 Aug 1.

Published in final edited form as: J Proteome Res. 2018 May 8;17(6):2205–2215. doi: 10.1021/acs.jproteome.8b00165

Table 1.

NCI-7 CompRef Cell Line Composition with Respective Histology and Gene Mutation Profile

cell line	tissue (histology)	gene mutation
NCI-H23	Lung (adenocarcinoma)	KRAS, TP53
RPMI-8226	Peripheral blood (plasmacytoma, myeloma)	KRAS, EGFR, TP53
T47D	Breast (carcinoma, ductal)	PI3KA, TP53
A549	Lung (adenocarcinoma)	KRAS, CDKN2A
COLO205	Colon (adenocarcinoma)	BRAF, SMAD4, APC, TP53
NCI-H226	Lung (mesothelioma, squamous cell)	CDKN2A
CCRF-CEM	Peripheral blood (leukemia, acute lymphoblastic)	KRAS, CDKN2A, PTEN, TP53