Table 3.

Summary of average firing rates in the cortex and pallidum before and after MPTP treatment

	CTX		GPe		GPi
	Normal	MPTP	Normal	MPTP	Normal	MPTP
Monkey T	5.3 ± 6.2 (n = 384)	7.1 ± 9.0 (n = 425)**	64.5 ± 30.9 (n = 103)	49.7 ± 28.9 (n = 247)***	69.1 ± 27.4 (n = 12)	66.8 ± 28.5 (n = 76)
Monkey W	5.3 ± 7.0 (n = 381)	4.3 ± 6.4 (n = 195)	68.3 ± 33.7 (n = 146)	51.7 ± 27.4 (n = 134)***	71.8 ± 32.6 (n = 63)	59.8 ± 20.8 (n = 13)

Discharge rates (spikes/s) are given as mean ± SD for MI, GPe, and GPi neurons. The rates are calculated based on the IStimI periods between the different frequency tests. We used the 10 s epochs that start 5 s after the last burst of the stimulation. n stands for the number of neurons on which the values are based. **p < 0.01, ***p < 0.001 significant differences of MPTP values versus corresponding normal values.