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Cross-linking experiment using MTS cross-linkers. Cross-linking experiments of double-Cys mt in microsomes and immunoblot analysis using anti-PS1NT antibody. Locations of Cys mutations are shown on the left. PS1 full-length protein, NTF, and cross-linked product (NTF–CTF heterodimer) are shown by black arrowheads, white arrowheads, and black arrows, respectively.
