Figure 7.

Increasing the extracellular [Ca²⁺] also leads to an increase in the cumulative EPSC amplitude during 100 Hz trains. A–C, EPSC traces in response to 100 Hz trains (A), plot of EPSC amplitudes (B), and cumulative EPSC amplitude plot (C), both for the control condition (2 mm [Ca²⁺]) and after applying 4 mm [Ca²⁺]. A, Inset, The first five EPSCs at an expanded time scale. Note that the increase in cumulative EPSC amplitude mostly results from the increased first to fourth EPSC amplitudes. D, Time course of the increase of the first EPSC amplitude (filled symbols) and of the cumulative EPSC amplitude (open symbols). Data in A–D are from the same cell.