Table 1.

Characteristics of secretory spikes from WT and CgA-KO mice

	I max (pA)	Q (pC)	t 1/2 (ms)	M (nA/s)	Ft1 (ms)	Ft2 (ms)	nspikes	ncells
WT	43.0 ± 3.6	0.67 ± 0.08	14.7 ± 2.3	15.8 ± 2.4	17.7 ± 1.6	38.4 ± 2.6	438	10
CgA-KO	42.3 ± 6.0	0.44 ± 0.04**	9.8 ± 0.7*	14.7 ± 2.4	12.9 ± 1.9*	31.0 ± 2.6*	555	9

For an explanation, see Materials and Methods and Segura et al. (2000). Shown are results from one typical experiment from a culture of both cell strains performed in parallel. Experiments were repeated using cells from five different cultures with similar results. The quantitative differences observed between data from WT from different cell cultures did not allow pooling data. Data are expressed in the units described.

*p < 0.05; **p < 0.01 (Mann–Whitney U test).