Figure 6.
Pharmacological manipulations disrupt the refinement of terminal fields. Samples of digit 4 terminations in P21 animals treated with either vehicle (left) or MK-801 (middle) and P2 animals (right; scaled to P21 size) as a reference. Top and bottom panels in each treatment group show the results obtained from two different animals. Mediolateral (Med-Lat) positions from midline of the terminal foci (x-marked) in individual animals are plotted below. Note the large interindividual variation in MK-801-treated animals and in P2 pups.