Table 2.
Temporal changes in mean arterial blood pressure and phrenic burst frequency in rats intrathecally injected with aCSF or 25 nm okadaic acid (25 nm OK)
Treatment (Trt) | Mean arterial blood pressure |
Burst frequency |
||||
---|---|---|---|---|---|---|
Baseline | Trt | 60 min post-Trt | Baseline | Trt | 60 min post-Trt | |
TC (aCSF) | 113 ± 6 | 114 ± 5 | 108 ± 5 | 44 ± 2 | 42 ± 2 | 46 ± 2 |
TC (25 nm OK) | 117 ± 6 | 116 ± 6 | 106 ± 5 | 41 ± 3 | 40 ± 3 | 45 ± 2 |
IH (aCSF) | 113 ± 5 | 69 ± 6* | 103 ± 5* | 38 ± 3 | 49 ± 2* | 42 ± 2 |
IH (25 nm OK) | 106 ± 9 | 73 ± 13* | 94 ± 10 | 41 ± 1 | 56 ± 3* | 41 ± 3 |
SH (aCSF) | 114 ± 5 | 68 ± 8* | 103 ± 4* | 43 ± 2 | 51 ± 2* | 46 ± 3 |
SH (25 nm OK) | 112 ± 6 | 82 ± 8* | 99 ± 4* | 38 ± 3 | 53 ± 2* | 44 ± 4* |
SH (25 nm OK) (methysergide) | 100 ± 9 | 69 ± 12* | 99 ± 8 | 40 ± 3 | 49 ± 4* | 43 ± 5 |
TC, Time control; OK, okadaic acid.
*Significantly different from baseline within treatment group.