Figure 2.

Gene expression level of cannabinoid receptor-interacting protein CRIP1a, but not CRIP1b, is reduced in the sclerotic epileptic hippocampus. A, CRIP1a mRNA level is significantly decreased in the sclerotic epileptic hippocampus (n = 6) compared with control values (n = 7). In contrast, the decrease in the nonsclerotic hippocampus (n = 7) did not reach significance. The direction and magnitude of expression level changes in the sclerotic hippocampus were identical in parallel experiments using two distinct housekeeping genes, β-actin and GAPDH. B, In contrast, CRIP1b mRNA levels did not differ significantly between nonsclerotic and sclerotic epileptic hippocampi compared with control values. Data are presented as mean expression ratio ± SEM. *p < 0.05.