Table 4.
Afterdischarge duration during kindling in ICER mutant mice
| Mice | First stimulation (s) | Convulsive stage |
||
|---|---|---|---|---|
| Stage 1 (s) | Stage 3 (s) | Fully kindled (s) | ||
| ICER-I-15 | ||||
| Non-TG (12) | 9.5 ± 2.7 | 16.4 ± 2.7 | 19.8 ± 2.2 | 23.4 ± 1.4 |
| TG (10) | 7.7 ± 1.5 | 11.5 ± 2.8 | 20.3 ± 1.4 | 28.5 ± 3.4 |
| ICER-II | ||||
| Non-TG (11) | 13.3 ± 1.4 | 16.0 ± 0.5 | 22.1 ± 2.2 | 22.6 ± 1.4 |
| TG (18) | 14.2 ± 1.5 | 13.8 ± 1.7 | 20.4 ± 1.0 | 26.3 ± 2.4 |
| ICER-KO | ||||
| WT (23) | 13.5 ± 1.4 | 14.0 ± 1.0 | 22.0 ± 1.2 | 25.7 ± 1.8 |
| KO (16) | 12.4 ± 1.7 | 15.3 ± 1.7 | 18.6 ± 1.6 | 25.5 ± 2.9 |
Duration of ADs was measured as described in Materials and Methods. Convulsive stage was determined according to the descriptions of Racine (1972) (see also Materials and Methods). AD values shown are averages ± SEM. Number of mice per group is indicated in parentheses.