Figure 6.

The incidence of microhemorrhage is mitigated by dose. a, Study A: the mean hemosiderin rating of the 3D6 group at 3 mg/kg was significantly higher than the TY11–15 group, and no significant difference was seen between the 266 and TY11–15 groups. b, Study B: the two lower-dose groups did not differ from the control, and the mean hemosiderin rating was significantly higher in the 3D6 3 mg/kg group compared with the TY11–15 and the 0.3 and 0.1 mg/kg 3D6 groups. Hemosiderin ratings 0–3 are represented by the white and hatched bars from left to right in each group. For studies A and B, all FET p values <0.025 and <0.0125, respectively, are statistically significant using the Hochberg method of multiple comparisons.