Table 1.

fMRI signal increases and decreases during the observation of painful stimuli

	Cluster level		Voxel level		MNI coordinates (mm)			Talairach coordinates (mm)
	k	p	z	p	x	y	Z	x	y	z
Brain areas displaying selective fMRI signal increases during the observation of painful stimuli (P − N)
pACC (BA24/32)	48	0.006	4.16	< 0.001	0	28	2	0	27	0
			3.94	< 0.001	10	36	−2	10	35	−3
L postcentral gyrus	57	0.003	3.86	< 0.001	−62	−20	18	−61	−19	18
			3.63	< 0.001	−66	−14	24	−65	−12	23
Brain areas displaying selective fMRI signal decreases during the observation of painful stimuli (N − P)
R S/M frontal gyrus (BA 10, 11)	114	0.000	4.20	< 0.001	32	60	−8	32	58	−10
			3.67	< 0.001	26	66	4	26	64	0
			3.28	0.001	26	56	−12	26	54	−13
R middle frontal gyrus (BA 10, 11, 47)	38	0.012	4.25	< 0.001	46	52	−8	46	50	−9
R middle frontal gyrus (BA 6)	59	0.003	5.30	< 0.001	22	10	68	22	13	62
R inferior parietal lobule (BA 40)	113	0.000	4.14	< 0.001	60	−48	40	59	−45	39
			3.81	< 0.001	52	−52	50	51	−48	48
			3.72	< 0.001	50	−50	42	50	−47	41
R medial parietal cortex/superior parietal lobule (BA 7)	81	0.001	3.97	< 0.001	16	−64	56	16	−59	55
			3.50	< 0.001	8	−60	58	8	−55	56
			3.35	< 0.001	8	−70	58	8	−65	57
R angular gyrus (BA 39)	28	0.027	3.52	< 0.001	38	−80	28	38	−76	30
R medial parietal cortex (BA 7)	121	0.000	4.61	< 0.001	16	−82	44	16	−77	44

R, Right; L, left; BA, Brodmann area.