Figure 8.

Activity of fin motoneurons at the onset of NMDA-induced fictive locomotion. A–D, Membrane potential modulation in four different fMNs, respectively at 3 (A), 10 (B), 15 (C), and 25 (D) min after the onset of superfusion with 150 μm NMDA. On the right-hand side of each recording the waveform correlations are shown: the black curves belong to the correlation between fMN and the ipsilateral ventral root; the red curves belong to the correlation between the two contralateral ventral root recordings shown on the left. D, E, Membrane potential modulation of a fMN recorded at 10 (D) then 25 (E) min after NMDA application when the regular out-of-phase membrane potential modulation is established. Please note that during the rather irregular activity on both sides of the spinal cord occurring briefly after the start of NMDA superfusion, fMNs are depolarized in phase with the ipsilateral ventral root (A–D).