Figure 6.

Neuropsin-independent late associativity was blocked by an LVDCC inhibitor. A, Two tetanus-induced tagging occurred after four trains of 100 Hz tetanus in S0 in KO slices. An fEPSP in S0 to which strong tetanus was applied (red filled circles) evoked stable L-LTP in S1-stimulated two tetanus (red open circles). B–D, Late associativity was not blocked by bath application of GRGDSP (B) and cytochalasin D (C) but was clearly blocked by nitrendipine (D). The black bar indicates the period of drug administration. Calibration: 1 mV, 10 ms. Inset traces show sample fEPSPs recorded during the baseline (a) period and 180 min (b) after stimulation at S1. Black short vertical bars indicate tetanic trains, respectively.