Figure 7.

Frequency responses of tonic and phasic compartmental models of 2°VNs superimposed on magnitude and phase data used for parameter estimation. A, C, Impedance and phase functions of tonic (A) and phasic 2°VNs (C) at two different membrane potentials, computed from published data (Beraneck et al., 2007). Gray curves indicate data and black curves are tonic and phasic neuronal model fits using parameter estimation methods described previously (Saint Mleux and Moore, 2000). For cell parameter values, see the supplemental material (available at www.jneurosci.org as supplemental material). B, D, Reconstruction of real-time current step responses of the tonic (B) and the phasic model neuron (D) using the compartmental models with respective parameters; the asymmetry between depolarizing and hyperpolarizing responses of the phasic neuron model (D) as well as the characteristic initial transient in response to positive current steps (D, asterisk) matches the real data (Straka et al., 2004).