Figure 5.

Effect of chronic fluoxetine treatment in adult WTneoSSRI mice. Immobility total duration is measured in WTneoSSRI mice receiving fluoxetine in drinking water (fluox; n = 14) or plain water (water; n = 9) in their bottle; the x-axis represents baseline (Bsl) tests and the days of test sessions (D7–D30) or of withdrawal (W10–W12). Values plotted are mean ± SEM. *p < 0.05, significant difference between groups; ^#p < 0.05, within-group significant difference with Bsl (paired test); °p < 0.05, within-group significant difference from Bsl and D30.