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. 2019 May 16;188(8):1475–1483. doi: 10.1093/aje/kwz102

Table 3.

Lagged Associations of Diarrhea Incidence With Recurrent Gatherings Hosted Among 17 Communities, Stratified by Community Engagement, Esmeraldas, Ecuador, 2004–2007

Hosting Exposure IRR CIa qb Ppermutec No. of Village-Weeksd
Nonee 1.00 Referent 1,075
Low-engagement gatherings
 Same week 1.01 0.74, 1.37 0.95 0.93 276
 1 week prior 1.13 0.94, 1.34 0.18 0.18 281
 2 weeks prior 1.14 0.92, 1.41 0.19 0.15 275
 3 weeks prior 1.05 0.75, 1.46 0.73 0.67 276
High-engagement gatherings
 Same week 0.86 0.51, 1.45 0.59 0.40 79
 1 week prior 1.29 0.97, 1.71 0.07 0.09 80
 2 weeks prior 1.51 1.09, 2.10 0.01 0.007 82
 3 weeks prior 1.4 0.85, 2.30 0.18 0.07 81
Uncategorized gatherings
 Same week 0.89 0.56, 1.40 0.59 0.44 122
 1 week prior 1.17 0.83, 1.66 0.39 0.22 108
 2 weeks prior 1.25 0.88, 1.76 0.19 0.08 125
 3 weeks prior 1.07 0.74, 1.54 0.70 0.66 124

Abbreviations: CI, confidence interval; IRR, incidence rate ratio.

a Confidence intervals were adjusted to ensure a false discovery rate of ≤0.05 and correspond to a marginal confidence level of 99.25%. See Methods and Web Appendix 3.

bq values, which represent the minimum false discovery rate if the threshold for declaring significance includes a parameter, were estimated via the Benjamini and Hochberg procedure (Web Appendix 3).

c Proportion of parameter estimates more extreme than the observed value under 10,000 permutations of end dates for each gathering and gathering sets between villages.

d Number of village-weeks in exposure category.

e The reference group is the set of village-weeks in which no gathering was hosted 0–3 weeks prior.