Ang II potentiates mechanosensitivity via the PLC-PKC pathway. Bar graphs show the mean (±SEM) values of MI recorded under various conditions. A, Values of MI in control (−Ang II; open bars) vs Ang II (+Ang II; filled bars) in vehicle (DMSO)-treated cells (Control) and in the presence of the PLC inhibitor U-73122. B, Values of MI observed in the absence (−Ang II; open bars) and presence (+Ang II; filled bars) of Ang II, in cells treated with vehicle (control) or Chel. C, Values of MI observed in the absence (−Ang II; open bars) and presence (+Ang II; filled bars) of Ang II, in cells patched with normal internal medium (Control) or medium containing 10 mm BAPTA. *p < 0.05. n.s., Difference not statistically significant.