Table 5.

Summary of behavioral effects seen in adult PN-antidepressant-treated mice

Arrows indicate statistically significant increases or decreases in the sensitive measures of the behavioral tests (drug vs vehicle): exploratory activity in the open field test (OF) and elevated plus maze (EPM), latency to feed in the NSF test, latency to feed and percentage inhibition of food consumption in the NIH test, and latency to escape in the shock escape test (SE). Solid arrows indicate that all sensitive measures in the respective test were affected; dashed arrows indicate that one of two sensitive measures was affected. Open cells indicate that drug treatment had no effect on the respective measures.