Table 1.

Baseline parameters in WT and Lmx1b^f/f/p mice

Parameter	Wild type	Lmx1bf/f/p
Age (d)	181.3 ± 14.4	167.9 ± 17.8
Body weight (gm)	31.4 ± 1.7	27.6 ± 1.8
TCore (°C)	38.2 ± 0.2	37.9 ± 0.3
VE (ml · min−1 · gm−1)	0.74 ± 0.05	0.68 ± 0.07
F (breath · min−1)	144.5 ± 4.5	119.2 ± 7.2*
VT (μl · breath−1 · gm−1)	5.16 ± 0.35	5.75 ± 0.38
VT/TI (ml · breath−1 · s−1)	1.26 ± 0.09	0.74 ± 0.52**
VO2 (ml O2 · min−1 · g−1)	0.048 ± 0.004	0.045 ± 0.004
VE/VO2	16.3 ± 1.5	15.7 ± 1.3
Arterial pH	7.305 ± 0.026	7.299 ± 0.029
PACO2 (mmHg)	41.5 ± 1.3	42.2 ± 1.7

All values are mean ± SEM. F, Frequency; V_T/T_I, ventilatory drive. All measurements were obtained while breathing room air at an ambient temperature of 30°C. Comparisons were made with a unpaired t test.

*p < 0.05;

**p< 0.001.