Figure 4.
CSA-CONT normalizes the number of proliferating cells and BrdU+ adult-generated neurons in the SGZ but increases posterior DCX+ cells. A, Quantitative analysis of Ki-67+ cells revealed no significant change in any region analyzed in the number of proliferating cells after CSA-CONT. B, Quantitative analysis of BrdU+ cells revealed no change in the number of surviving cells in the SGZ after CSA-CONT. C, CSA-CONT did not change the percentage of BrdU+ SGZ cells colocalizing with the neuronal marker NeuN or displaying a punctate BrdU staining pattern. D, Quantitative analysis of the density of DCX+ cells in the SGZ after CSA-CONT revealed a significant increase in the number of DCX+ cells in the posterior SGZ after CSA-CONT. E, CSA-CONT did not change the dendritic morphology of DCX+ cells in the posterior SGZ. Data for A–E are presented as the mean ± SEM. *p = 0.05. Hab, Habenula.