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. 2008 Dec 31;28(53):14511–14521. doi: 10.1523/JNEUROSCI.3417-08.2008

Figure 6.

Figure 6.

Memory impairment in TTBK1-Tg mice as determined by radial arm water maze (RAWM). A, B, Mice at 9–10 months of age (non-Tg and TTBK1-Tg) were tested by 10-d RAWM test consisting of 5 trials (T1–T5) of hidden platform tests per day for 10 d. After T1 through T4 the mouse is returned to its cage for 30 min and then administered a retention trial (T5). The time and errors taken by the mouse to reach the platform are recorded as escape latency (A) or errors (B). *p < 0.05, **p < 0.01, or ***p < 0.001 as determined by two-way repeated-measure ANOVA with Bonferroni posttest (n = 9 for non-Tg and 10 for TTBK1-Tg group).