Figure 2.
Forskolin-induced LTP causes a change in PPF and CV index. A, B, Potentiation of EPSCs recorded during application of forskolin and the corresponding alteration of PPF (0.84 ± 0.05, n = 8; p < 0.05). Calibration: 150 pA, 20 ms. Please note the corresponding decrease in the input resistance during washin of forskolin (closed circles). However, after washout the input resistance returned to baseline values, while the EPSC amplitude remained potentiated. C, The calculated values for CV2(forskolin)/CV2(control) plotted against ratio of the EPSC(control)/EPSC(forskolin) fell close to the bisecting line consistent with a presynaptic effect of forskolin.