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. 2008 Dec 31;28(53):14358–14362. doi: 10.1523/JNEUROSCI.4973-08.2008

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Copyright © 2008 Society for Neuroscience 0270-6474/08/2814358-05$15.00/0

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Figure 4. — Forskolin and cBIMPS occlude activity-dependent LTP in burst firing neurons. A, C, In bursting cells forskolin-induced enhancement of EPSCs prevented tetanus-induced LTP (1.07 ± 0.13, n = 6). B, D, Sp-5,6-DCl-cBIMPS mimicked and occluded tetanus-induced LTP in bursting neurons (1.23 ± 0.09, n = 5). E, In forskolin-preincubated slices, regular firing but not bursting cells express activity-dependent LTP upon tetanic stimulation (1.76 ± 0.31, n = 6). F, Blockade of PKA by Rp-8-CPT-cAMP prevented LTP in bursting neurons (1.14 ± 0.10, n = 6).