Ectopic expression of TH-positive neurons. A–F, Serial caudorostral transverse sections of an E18 medulla of Lbx1GFP/+ (A–C) and Lbx1GFP/GFP (D–F) mice labeled for TH (red) and GFP (green). Note the intense somatic and neuropilar staining in the noradrenergic structures of A1/C1, A2, C2/C3 of Lbx1GFP/GFP mice. In addition, there is ectopic localization of TH+ neurons along the midline and in the reticular formation. Scale bar: A–F, 500 μm.