Figure 3.

GABA_A receptor-mediated sIPSCs and mISPCs do not differ between D₁⁺ and D₂⁺ MSNs. A, Representative traces showing sIPSCs in a D₁⁺ MSN (top) and a D₂⁺ MSN (bottom). Calibration: 1 s, 25 pA. Summary of the mean amplitude (B), frequency of events (C), tau values (D), and rise time (E) for sIPSCs in D₁⁺ and D₂⁺ MSNs. sIPSC values were measured using KCl internal (black bars; n = 6 and 12) and with CsCl internal (white bars; n = 8 and 10) from D₁⁺ and D₂⁺ MSNs, respectively. G, Representative traces demonstrate mIPSCs in a D₁⁺ MSN (top) and a D₂⁺ MSN (bottom). Calibration: 1 s, 25 pA. Summary of the mean amplitude (H), frequency of events (I), tau values (J), and rise time (K) for mIPSCs in D₁⁺ and D₂⁺ MSNs. mIPSCs values were measured from the same cells represented in B–D using KCl internal (black bars) and CsCl internal (white bars) by subsequent application of TTX (500 nm), NBQX (5 μm), and strychnine (500 nm). Cumulative probability plots for the average mIPSC (F), amplitude, and interevent interval (L) from D₁⁺ MSNs (dashed black line; n = 9) and D₂⁺ MSNs (solid gray line; n = 10) recorded with CsCl internal.