Table 1.

Red flags for MYH9-RD in the kidney disease patient

Family history of ITP, bleeding, kidney disease or deafness

ITP AND glomerular nephropathy

Macrothrombocytopenia AND Döhle body-like granulocyte inclusions

Glomerular nephropathy AND sensorineural deafness AND cataracts

‘Alport syndrome-like’ AND thrombocytopenia

Steroid-resistant FSGS AND thrombocytopenia

Steroid-resistant FSGS AND deafness

Early onset cataracts

Frequent haematomas

Spontaneous haemorrhages AND/OR excessive bleeding provoked by haemostatic challenges as trauma or surgery (post-partum, road accident, anti-platelet agents)

Unexplained liver enzyme abnormalities AND kidney disease