Figure 8.
Lack of correlation between variations of Rinput (ΔRinput) and variations of cc (Δcc) or Gj (ΔGj) in experiments testing the involvement of a β-AR/cAMP/PKA-mediated pathway. A, Summary plot relating ΔRinput to Δcc. The dotted line is the regression line weighted according to the SEM of the data points (r = −0.11; n = 7; p > 0.05). Experiments are identified by letters as follows: a, effect of noradrenaline (Δcc from n = 14 bidirectional connections, and ΔRinput from n = 14 cells; data from Fig. 2A); b, effect of H89 (Δcc from n = 14 bidirectional connections, and ΔRinput from n = 14 cells; data from Fig. 5A); c, effect of forskolin (Δcc from n = 20 bidirectional connections, and ΔRinput from n = 20 cells; data from Fig. 3A); d, effect of MDL12330A recorded with Cs-methylsulfate-QX-314-based electrodes (Δcc from n = 10 bidirectional connections, and ΔRinput from n = 10 cells; data from Fig. 7A); e, effect of isoproterenol (Δcc from n = 10 bidirectional connections, and ΔRinput from n = 10 cells; data from Fig. 2B); f, effect of MDL12330A recorded with K-methylsulfate-based solutions (Δcc from n = 8 bidirectional connections, and ΔRinput from n = 8 cells; data from Fig. 4); g, effect of forskolin in cells repatched with control electrodes (Δcc from n = 18 bidirectional connections, and ΔRinput from n = 18 cells; data from Fig. 6B). Error bars are SEM. B, Similar plot showing the lack of correlation between ΔRinput and ΔGj (r = −0.17; n = 7; p > 0.05).