Figure 2.

Motor function recovery after unilateral sciatic nerve crush lesion. A gradual recovery of motor function was measured using the sciatic functional index based on the comparison of footprint parameters of the regenerating hindpaw with the contralateral paw. Wild-type mice (wt; white squares) reached full recovery on postlesion day 14, whereas β4^−/− mice (β4^−/−; black circles) did not reach full recovery until postlesion day 20. Motor function recovery was significantly delayed in β4^−/− mice (F_(1,32) = 12.316; p < 0.001).