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GABAARs containing α5 or δ subunits mediate tonic inhibitory currents in hippocampal neurons. A, Whole-cell voltage-clamp recording of a CA1 PC (Vh = −70 mV). Top lines indicate the perfusion of L-655,708 and BMI. Right, Fit to the all-points histogram from segments of each of the three conditions. B, Whole-cell voltage-clamp recordings from Gabra 5/Gabrd−/− CA1 and CA3 PC, DGGC and a molecular layer interneuron (Vh = −70 mV). Right, Same as in A.
